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Product Name
Human CFL1 / cofilin (His Tag) recombinant protein
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Description
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation.
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Protein name
Cofilin-1
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Protein short names
HEL-S-15; COFILIN 1; COFILIN; COF; COFILIN-1; COFILIN 1 (NON-MUSCLE); 18 KDA PHOSPHOPROTEIN; NON-MUSCLE ISOFORM; P18; CFL1; CFL; NON-MUSCLE ISOFORM; N-COFILIN; AA959946; NON-MUSCLE
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Uniprot ID
P23528
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Gene Name
CFL1; CFL
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human CFL1 (P23528) (Met1-Leu166) was expressed with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CFL1 consists of 181 amino acids and predicts a molecular mass of 20.3 KDa. It migrates as an approximately 21 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human CFL1 / N-cofilin Protein (His Tag) SDS-PAGE
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