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  • Anti-Casein Kinase 1 alpha Rabbit antibody

Anti-Casein Kinase 1 alpha Rabbit antibody

Cat.#: 168868

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-Casein Kinase 1 alpha Rabbit antibody
  • Documents
  • Description
    Casein Kinase 1 alpha Rabbit monoclonal antibody
  • Tested applications
    WB, IP
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    CK1; CK1a; CKIa; HLCDGP1; PRO2975; HEL-S-77p antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human Casein Kinase 1 alpha
  • Clonality
    Monoclonal antibody
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    1:1000

    1:20

  • Validations

    Western blot detection of Casein Kinase 1 alpha in K562,Rat Brain,C6,Hela cell lysates using Casein Kinase 1 alpha Rabbit mAb(1:1000 diluted).Predicted band size:39kDa.Observed band size:34kDa.

    Western blot detection of Casein Kinase 1 alpha in K562,Rat Brain,C6,Hela cell lysates using Casein Kinase 1 alpha Rabbit mAb(1:1000 diluted).Predicted band size:39kDa.Observed band size:34kDa.

  • Background
    Swiss-Prot Acc.P48729.Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688).
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"