-
Product Name
Anti-Beclin 1 (4F4) Mouse antibody
- Documents
-
Description
Beclin 1 (4F4) Mouse monoclonal antibody
-
Tested applications
WB
-
Species reactivity
Human, Mouse, Rat, Monkey, Hamster
-
Alternative names
APG6;ATG 6;ATG6;ATG6 autophagy related 6 homolog;Bcl-2-interacting protein beclin;Beclin 1 (coiled coil moesin like BCL2 interacting protein);Beclin 1 autophagy related;Beclin-1;Beclin1;BECN 1;BECN1;BECN1_HUMAN;Coiled coil myosin like BCL2 interacting pro antibody
-
Isotype
Mouse IgG1
-
Preparation
Antigen: Purified recombinant human Beclin 1 protein fragments expressed in E.coli.
-
Clonality
Monoclonal
-
Formulation
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4 150 mM NaCl) with 0.02% sodium azide 50% glycerol
-
Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
-
Applications
WB: 1/1000
-
Validations
Western blot detection of Beclin 1 in Hela,3T3,C6,COS7,CHO-K1,Rat brain and Jurkat cell lysates using Beclin 1 mouse mAb (1:1000 diluted).Predicted band size:52KDa.Observed band size:55KDa.
-
Background
Swiss-Prot Acc.Q14457.Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.
-
References
- Nrf2 protects against acute lung injury and inflammation by modulating TLR4 and Akt signaling.Effect of metformin on human periodontal ligament stem cells cultured with polydopamine-templated hydroxyapatite
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"