Anti-Beclin 1 (4F4) Mouse antibody

Cat.#: 168125

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Product Information

  • Product Name
    Anti-Beclin 1 (4F4) Mouse antibody
  • Documents
  • Description
    Beclin 1 (4F4) Mouse monoclonal antibody
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse, Rat, Monkey, Hamster
  • Alternative names
    APG6;ATG 6;ATG6;ATG6 autophagy related 6 homolog;Bcl-2-interacting protein beclin;Beclin 1 (coiled coil moesin like BCL2 interacting protein);Beclin 1 autophagy related;Beclin-1;Beclin1;BECN 1;BECN1;BECN1_HUMAN;Coiled coil myosin like BCL2 interacting pro antibody
  • Isotype
    IgG1
  • Preparation
    Antigen: Purified recombinant human Beclin 1 protein fragments expressed in E.coli.
  • Clonality
    Monoclonal
  • Formulation
    Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4 150 mM NaCl) with 0.02% sodium azide 50% glycerol
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

  • Validations

    Western blot detection of Beclin 1 in Hela,3T3,C6,COS7,CHO-K1,Rat brain and Jurkat cell lysates using Beclin 1 mouse mAb (1:1000 diluted).Predicted band size:52KDa.Observed band size:55KDa.

    Western blot detection of Beclin 1 in Hela,3T3,C6,COS7,CHO-K1,Rat brain and Jurkat cell lysates using Beclin 1 mouse mAb (1:1000 diluted).Predicted band size:52KDa.Observed band size:55KDa.

  • Background
    Swiss-Prot Acc.Q14457.Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.
  • References
    • Nrf2 protects against acute lung injury and inflammation by modulating TLR4 and Akt signaling.Effect of metformin on human periodontal ligament stem cells cultured with polydopamine-templated hydroxyapatite

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"