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Product Name
Mouse ACE2 / Angiotensin-Converting Enzyme 2 (His Tag) recombinant protein
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Description
Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. May have a protective role in acute lung injury.
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Protein name
Angiotensin-converting enzyme 2
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Protein short names
DKFZP434A014; ACEH; ACE2; RP23-330O24.1; 2010305L05RIK
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Uniprot ID
Q8R0I0
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Gene Name
Ace2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse ACE2 isoform 1 (Q8R0I0-1) extracellular domain (Met 1-Thr 740) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse ACE2 comprises 734 amino acids and has a predicted molecular mass of 85 kDa. As a result of glycosylation, it migrates as an approximately 110 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Mouse ACE2 / Angiotensin-Converting Enzyme 2 Protein (His Tag) SDS-PAGE
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