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  • Rat ACE2 / Angiotensin-Converting Enzyme 2 (His Tag) recombinant protein

Rat ACE2 / Angiotensin-Converting Enzyme 2 (His Tag) recombinant protein

Cat.#: 500718

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Product Information

  • Product Name
    Rat ACE2 / Angiotensin-Converting Enzyme 2 (His Tag) recombinant protein
  • Documents
  • Description
    Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function.
  • Protein name
    Angiotensin-converting enzyme 2
  • Protein short names
    RP23-330O24.1; 2010305L05RIK; ACE2; ACEH; DKFZP434A014
  • Uniprot ID
    Q5EGZ1
  • Gene Name
    Ace2
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the rat ACE2 (Q5EGZ1) extracellular domain (Met 1-Thr 740) was fused with a polyhistidine tag at the C-terminus.
  • Protein Species
    Rat
  • Molecular weight
    The recombinant rat ACE2 comprises 734 amino acids and predicts a molecular mass of 85 kDa. The apparent molecular mass of the rat ACE2 is approximately 105-115 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 97 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH, (R&D Systems, Catalog # ES007). The specific activity is >300 pmol/min/μg.
  • Validations

    Rat ACE2 / Angiotensin-Converting Enzyme 2 Protein (His Tag) SDS-PAGE

    Rat ACE2 / Angiotensin-Converting Enzyme 2 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"