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Product Name
Canine CD40/TNFRSF5 recombinant protein
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Description
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).
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Protein name
Tumor necrosis factor receptor superfamily member 5
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Protein short names
RP23-428M13.1; TRAP; GP39; MGC9013; BP50; HIGM1; CD40; TNFRSF5; IGM; T-BAM; IMD3; AI326936; CDW40; P50
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Uniprot ID
Q7YRL5
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Gene Name
CD40; TNFRSF5
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the canine CD40 (Q7YRL5) (Met1-Ala194) was expressed with six amino acids (LEVLFQ) at the C-terminus.
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Protein Species
Canine
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Molecular weight
The recombinant canine CD40 is a disulfide-linked homodimer. The reduced monomer comprises 181 amino acids and has a predicted molecular mass of 19.9 kDa. The apparent molecular mass of the protein is approximately 28-32 kDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Canine CD40 / TNFRSF5 Protein SDS-PAGE
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