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Product Name
Human OX40/CD134 (His Tag) recombinant protein
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Description
Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity.
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Protein name
Tumor necrosis factor receptor superfamily member 4
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Protein short names
OX40; LY-70; ACT35; RP5-902P8.3; IMD16; TXGP1; TNFRSF4; CD134; TXGP1L
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Uniprot ID
P43489
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Gene Name
TNFRSF4; TXGP1L
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain (Met 1-Ala 216) of human TNFRSF4 (NP_003318.1) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human TNFRSF4 consists of 199 amino acids after removal of the signal peptide and has a predicted molecular mass of 21.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh TNFRSF4 is approximately 40-45 kDa due to glycosylation.
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Purity
> 90 % as determined by SDS-PAGE
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Activity
1. Measured by its binding ability in a functional ELISA.
2. Immobilized human TNFRSF4-his (Cat: 501432) at 2 μg/mL (100 μl/well) can bind human TNFSF4/mFc (cat: 500243), The EC50 of human TNFSF4/mFc is 29 ng/mL. -
Validations
Human TNFRSF4 / OX40 / CD134 Protein (His Tag) SDS-PAGE
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