Mouse Tnfrsf4/Ox40/Txgp1 (Fc tag) recombinant protein

Cat.#: 519490

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Product Information

  • Product Name
    Mouse Tnfrsf4/Ox40/Txgp1 (Fc tag) recombinant protein
  • Documents
  • Description
    OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.
  • Protein name
    tumor necrosis factor receptor superfamily, member 4(Tnfrsf4)
  • Protein short names
    Ox40; Txgp1
  • Uniprot ID
    P47741
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Mouse Tnfrsf4/Ox40/Txgp1 Val20-Pro211 is expressed with a Fc tag at the C-terminus.
  • Protein Species
    Mouse
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Mouse Tnfrsf4/Ox40/Txgp1 (Fc tag) recombinant protein

    Mouse Tnfrsf4/Ox40/Txgp1 (Fc tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"