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Product Name
Mouse TNFSF10/TRAIL/APO-2L (CD253) (aa 118-291, His Tag) recombinant protein
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Description
Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
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Protein name
Tumor necrosis factor ligand superfamily member 10
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Protein short names
TRAIL; APO2L; AI448571; APO-2L; TNFSF10; A330042I21RIK; LY81; CD253; TL2
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Uniprot ID
P50592
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Gene Name
Tnfsf10; Trail
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse TNFSF10 (P50592) (Pro 118-Asn 291) was expressed, with a polyhistide tag at the N-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse TNFSF10 consisting of 190 amino acids and has a calculated molecular mass of 22.2 kDa. rm TNFSF10 migrates as an approximately 22 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Mouse TNFSF10 / TRAIL / APO-2L Protein (aa 118-291, His Tag) SDS-PAGE
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