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  • Human TNFSF10/APO2L/TRAIL recombinant protein

Human TNFSF10/APO2L/TRAIL recombinant protein

Cat.#: 519083

Special Price 146.3 USD

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Product Information

  • Product Name
    Human TNFSF10/APO2L/TRAIL recombinant protein
  • Documents
  • Description
    Human TNFSF10 is a type II transmembrane protein with an intracellular N-terminus and a ‘TNF homology domain’ (THD) at the extracellular C terminus. TNFSF10 can interact with several distinct receptors. Two of these receptors that belongs to TNFR superfamily, DR4 (TRAIL-R1) and DR5 (TRAIL-R2/TRICK2), are plasma membrane proteins containing intracellular death domains essential for activating apoptosis. TNFSF10 is promising for cancer therapy because it is cytotoxic and activates apoptosis in the majority of malignant cells, but not in normal cells.
  • Protein name
    tumor necrosis factor superfamily member 10(TNFSF10)
  • Protein short names
    APO2L; TRAIL
  • Uniprot ID
    P50591
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human TNFSF10/APO2L/TRAIL Arg115-Gly281 is expressed.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human TNFSF10/APO2L/TRAIL recombinant protein

    Human TNFSF10/APO2L/TRAIL recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"