TSPAN1 antibody

Cat.#: 116440

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Product Information

  • Product Name
    TSPAN1 antibody
  • Documents
  • Description
    TSPAN1 Rabbit Polyclonal antibody. Positive IHC detected in human colon tissue. Positive WB detected in HeLa cells, COLO 320 cells, rat colon tissue. Observed molecular weight by Western-blot: 26-35kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human, Mouse, Rat; other species not tested.
  • Alternative names
    9030418M05Rik antibody; NET 1 antibody; RP11 322N21.1 antibody; Tetraspan NET 1 antibody; tetraspanin 1 antibody; Tetraspanin TM4 C antibody; TSPAN 1 antibody; TSPAN1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of TSPAN1 recombinant protein (Accession Number: NM_005727). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:1000

    IHC: 1:20-1:200

  • Validations

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:116440(TSPAN1 antibody) at dilution of 1:300

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:116440(TSPAN1 antibody) at dilution of 1:300

    Immunohistochemistry of paraffin-embedded human colon tissue slide using Catalog No:116440(TSPAN1 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human colon tissue slide using Catalog No:116440(TSPAN1 Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human colon tissue slide using Catalog No:116440(TSPAN1 Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human colon tissue slide using Catalog No:116440(TSPAN1 Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    TSPAN1 is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. Altered TSPAN1 expression has been associated with the progression in some neoplasms including hepatocellular carcinoma, colorectal, gastric and breast cancers (PMID: 20890423; 19437569; 18822690; 20680643).

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