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Product Name
TNRC4 antibody
- Documents
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Description
TNRC4 Rabbit Polyclonal antibody. Positive IHC detected in human testis tissue, human cerebellum tissue. Positive WB detected in mouse lung tissue, mouse spleen tissue. Observed molecular weight by Western-blot: 55 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
Bruno like protein 1 antibody; BRUNOL1 antibody; CAG repeat protein 4 antibody; CAGH4 antibody; CELF 3 antibody; CELF3 antibody; ERDA4 antibody; ETR 1 antibody; RNA binding protein BRUNOL 1 antibody; TNRC4 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TNRC4 recombinant protein (Accession Number: NM_001291106). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
mouse lung tissue were subjected to SDS PAGE followed by western blot with Catalog No:116158(TNRC4 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human cerebellum tissue slide using Catalog No:116158(TNRC4 Antibody) at dilution of 1:50 (under 40x lens)
Immunohistochemistry of paraffin-embedded human testis tissue slide using Catalog No:116158(TNRC4 Antibody) at dilution of 1:50 (under 40x lens)
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Background
TNRC4, also named as BRUNOL1, CAGH4, ERDA4, or TNRC4, is a 465 amino acid protein, which contains three RRM (RNA recognition motif) domains and belongs to the CELF/BRUNOL family. TNRC4 localizes in the nucleus and is expressed in brain. TNRC4 as a RNA-binding protein is involved in the regulation of pre-mRNA alternative splicing and mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing.
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