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Product Name
Human TNRC4 Recombinant protein (His tag)
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Description
RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA. {PubMed:11158314, PubMed:15009664}.
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Protein name
CUGBP Elav-like family member 3
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Protein short names
BRUNOL1; CAGH4; ERDA4; TNRC4
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Uniprot ID
H0Y623
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Gene Name
CELF3; BRUNOL1; CAGH4; ERDA4; TNRC4
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human CELF3 (NP_001278035.1) 180-352 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human TNRC4 SDS-PAGE
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