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Product Name
TNFRSF12A Polyclonal Antibody
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Description
Polyclonal antibody to TNFRSF12A
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Tested applications
WB
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Species reactivity
Human
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Alternative names
TNFRSF12A antibody; CD266 antibody; FN14 antibody; TWEAKR antibody; TNF receptor superfamily member 12A antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 28-129 of human TNFRSF12A (NP_057723.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
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Validations
Western blot - TNFRSF12A Polyclonal Antibody
Western blot analysis of extracts of HT-1080 cells, using TNFRSF12A antibody at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.
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Background
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"