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Product Name
Mouse tPA (Fc Tag) recombinant protein
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Description
Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events.
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Protein name
Tissue-type plasminogen activator
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Protein short names
T-PA; DKFZP686I03148; PLAT; TPA; D8ERTD2E; MGC18508; AW212668; AU020998
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Uniprot ID
P11214
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Gene Name
Plat
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse PLAT (P11214) (Ile309-Gln559) was was expressed with the fused Fc region of human IgG1 at the N-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse PLAT/Fc comprises 511 amino acids and has a predicted molecular mass of 56.4 kDa. The apparent molecular mass of the protein is approximately 57 kDa in SDS-PAGE under reducing conditions due to glycosylation.
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Purity
> 80 % as determined by SDS-PAGE
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Validations
Mouse tPA / PLAT Protein (Fc Tag) SDS-PAGE
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