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  • PLAT Polyclonal Antibody

PLAT Polyclonal Antibody

Cat.#: 166631

Special Price 174.2 USD

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Product Information

  • Product Name
    PLAT Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to PLAT
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse
  • Alternative names
    PLAT antibody; T-PA antibody; TPA antibody; tissue-type plasminogen activator antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-320 of human PLAT (NP_000921.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - PLAT Polyclonal Antibody

    Western blot - PLAT Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using PLAT antibody at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit ._Exposure time: 90s.

  • Background
    Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"