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Product Name
Tisotumab vedotin (Synonyms: HUMAXTFADC)
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Description
Anti-TF / Factor III / Tissue Factor / CD142 Antibody (Tisotumab vedotin)
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Tested applications
ELISA
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Species reactivity
Human TF / Factor III / Tissue Factor / CD142
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Alternative names
HUMAXTFADC antibody
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Isotype
IgG1
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Preparation
Recombinant expression and purified from CHO cells.
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Clonality
Monoclonal
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Formulation
0.1 M Pro-Ac, 20 mM Arg, pH 5.0
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Storage instructions
-80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions; Avoid repeated freeze-thaw cycles.
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Validations
SDS-PAGE
Anti-TF / Factor III / Tissue Factor / CD142 Antibody (tisotumab vedotin) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
SEC-HPLC
The purity of Anti-TF / Factor III / Tissue Factor / CD142 Antibody (tisotumab vedotin) is 99.08%, determined by SEC-HPLC.
HIC-HPLC
The drug-to-antibody ratio (DAR) of the Anti-Tissue Factor /CD142 Antibody (tisotumab vedotin) is 4.2.
Bioactivity: FACS
Human TF HEK293 cells were stained with tisotumab vedotin and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50 is 0.2781 ug/mL.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"