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Product Name
Human CD2 (His Tag) recombinant protein
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Description
CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
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Protein name
T-cell surface antigen CD2
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Protein short names
FLJ46032; SRBC; LY-37; LFA-2; T11; CD2; LY37; RP4-655N15.2
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Uniprot ID
Q53F96
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Gene Name
CD2; SRBC
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human CD2 (NP_001758.2) extracellular domain (Met 1-Asp 209) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CD2 consists of 196 amino acids and has a predicted molecular mass of 22.7 kDa. In SDS-PAGE under reducing conditions, rhCD2 magrates as an approximately 37 kDa band due to glycosylation.
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Purity
> 97 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA.
Immobilized human CD2-His at 10 μg/ml (100 μl/well) can bind human CD58-Fc (Cat:501121), The EC50 of human CD58-Fc (Cat:501121) is 0.04-0.1 μg/ml. -
Validations
Human CD2 Protein (His Tag) SDS-PAGE
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