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Product Name
Cynomolgus CD2 (Fc Tag) recombinant protein
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Description
CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function (By similarity).
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Protein name
T-cell surface antigen CD2
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Protein short names
SRBC; LY-37; T11; LFA-2; FLJ46032; CD2; RP4-655N15.2; LY37
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Uniprot ID
Q6SZ61
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Gene Name
CD2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the cynomolgus CD2 (Q6SZ61) (Met1-Asp209) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Cynomolgus
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Molecular weight
The recombinant cynomolgus CD2 comprises 423 amino acids and has a calculated molecular mass of 48.1 KDa. The apparent molecular mass of the protein is approximately 63 KDa in SDS-PAGE.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA.
Immobilized Cynomolgus CD58-His (Cat:503677) at 10 μg/ml (100 μl/well) can bind Cynomolgus CD2-Fc, The EC50 of Cynomolgus CD2-Fc is 0.06-0.14 μg/ml. -
Validations
Cynomolgus CD2 Protein (Fc Tag) SDS-PAGE
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