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Product Name
Rat Syndecan-1/SDC1/CD138 (Fc Tag) recombinant protein
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Description
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.
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Protein name
Syndecan-1
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Protein short names
CD138; AA409076; SYND; SYN-1; SDC; SSTN; SYNDECAN; AA408134; SYNDECAN-1; SDC1; SYND1
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Uniprot ID
P26260
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Gene Name
Sdc1; Synd1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat SDC1 (P26260) (Met1-Lys253) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat SDC1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 472 amino acids and has a predicted molecular mass of 51.2 kDa. The apparent molecular mass of the protein is approximately 92 kDa in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Activity
1. Measured by its binding ability in a functional ELISA. Immobilized human PTN (Cat:501387) at 10 μg/ml (100 μl/well) can bind rat SDC1-Fc (Cat:502988), The EC50 of rat SDC1-Fc (Cat:502988) is 0.35-0.81 μg/ml.
2. Measured by its binding ability in a functional ELISA. Immobilized mouse PTN (Cat:504073) at 10 μg/ml (100 μl/well) can bind rat SDC1-Fc, The EC50 of rat SDC1-Fc is 0.4-1.1 μg/ml. -
Validations
Rat Syndecan-1 / SDC1 / CD138 Protein (Fc Tag) SDS-PAGE
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