Rat Syndecan-1/SDC1/CD138 (His Tag) recombinant protein

Cat.#: 503501

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Product Information

  • Product Name
    Rat Syndecan-1/SDC1/CD138 (His Tag) recombinant protein
  • Documents
  • Description
    Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development. Syndecan-1/SDC1/CD138 has been shown to mediate cell adhesion to several ECM molecules, and to act as a coreceptor for fibroblast growth factors, potent angiogenic growth factors involved also in differentiation. Syndecan-1/SDC1/CD138 expression is reduced during malignant transformation of various epithelia, and this loss correlates with the histological differentiation grade of squamous cell carcinomas, lacking from poorly differentiated tumours. In squamous cell carcinomas of the head and neck, positive syndecan-1 expression correlates with a more favourable prognosis. Experimental studies on the role of Syndecan-1 in malignant transformation have shown that Syndecan-1/SDC1/CD138 expression is associated with the maintenance of epithelial morphology, anchorage-dependent growth and inhibition of invasiveness in vitro.
  • Protein name
    Syndecan-1
  • Protein short names
    SYND1; AA408134; SDC1; SYNDECAN-1; SYNDECAN; SSTN; SYN-1; SDC; SYND; AA409076; CD138
  • Uniprot ID
    P26260
  • Gene Name
    Sdc1; Synd1
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the rat SDC1 (P26260) (Met1-Lys253) was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    Rat
  • Molecular weight
    The recombinant rat SDC1 comprises 242 amino acids and predicts a molecular mass of 25.6 kDa. The apparent molecular mass of the recombinant protein is approximately 47 and 49 kDa in SDS-PAGE under reducing conditions due to glycosylation.
  • Purity
    (76+20) % as determined by SDS-PAGE
  • Validations

    Rat Syndecan-1 / SDC1 / CD138 Protein (His Tag) SDS-PAGE

    Rat Syndecan-1 / SDC1 / CD138 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"