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SULT2B1 antibody

Cat.#: 115832

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Product Information

  • Product Name
    SULT2B1 antibody
  • Documents
  • Description
    SULT2B1 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue, human placenta tissue. Positive IP detected in mouse skin tissue. Positive WB detected in mouse skin tissue. Observed molecular weight by Western-blot: 39 kDa
  • Tested applications
    ELISA, WB, IHC, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    Alcohol sulfotransferase antibody; HSST2 antibody; ST2B1 antibody; Sulfotransferase 2B1 antibody; SULT2B1 antibody; sult2b1a antibody; sult2b1b antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of SULT2B1 recombinant protein (Accession Number: NM_177973). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:200-1:1000

    IHC: 1:20-1:200

  • Validations

    mouse skin tissue were subjected to SDS PAGE followed by western blot with Catalog No:115832(SULT2B1 antibody) at dilution of 1:400

    mouse skin tissue were subjected to SDS PAGE followed by western blot with Catalog No:115832(SULT2B1 antibody) at dilution of 1:400

    Immunohistochemistry of paraffin-embedded human prostate cancer slide using Catalog No:115832(SULT2B1 Antibody) at dilution of 1:50. Heat mediated antigen retrieved with Citric acid buffer, pH6.0.

    Immunohistochemistry of paraffin-embedded human prostate cancer slide using Catalog No:115832(SULT2B1 Antibody) at dilution of 1:50. Heat mediated antigen retrieved with Citric acid buffer, pH6.0.

    IP Result of anti-SULT2B1 (IP:Catalog No:115832, 4ug; Detection:Catalog No:115832 1:400) with mouse skin tissue lysate 3200ug.

    IP Result of anti-SULT2B1 (IP:Catalog No:115832, 4ug; Detection:Catalog No:115832 1:400) with mouse skin tissue lysate 3200ug.

  • Background
    SULT2B1 is a member of hydroxysteroid sulfotransferase (SULT) family that catalyzes sulfonation of hormones and other molecules. SULT2B1 encodes two isoforms, SULT2B1a and SULT2B1b, that differ only at their amino termini but have distinct biochemical properties as well as tissue distribution. The human fetal brain appears to only express the SULT2B1a isoform, while SULT2B1b is the predominant hydroxysteroid sulfotransferase expressed in human skin. Northern blot analysis revealed SULT2B1a has a limited tissue distribution in liver, adrenal and stomach, whereas SULT2B1b can be detected in a variety of hormone-responsive tissues including placenta, ovary, uterus, and prostate. This antibody recognizes both of ULT2B1a and SULT2B1b.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"