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Product Name
SNRPE antibody
- Documents
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Description
SNRPE Rabbit Polyclonal antibody. Positive WB detected in human placenta tissue, human brain tissue. Positive IHC detected in human brain tissue, human hepat℃irrhosis tissue. Observed molecular weight by Western-blot: 11kd
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Sm E antibody; Sm protein E antibody; SME antibody; snRNP E antibody; SNRPE antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of SNRPE recombinant protein (Accession Number: NM_003094). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
human placenta tissue were subjected to SDS PAGE followed by western blot with Catalog No:115463(SNRPE Antibody) at dilution of 1:600
Immunohistochemical of paraffin-embedded human brain using Catalog No:115463(SNRPE antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human brain using Catalog No:115463(SNRPE antibody) at dilution of 1:50 (under 40x lens)
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Background
The snRNP E (SNRPE)protein is one of several proteins associated with the U family of small nuclear RNAs that are involved in RNA processing. It functions in the U7 snRNP complex that is involved in histone 3'-end processing and also associated with snRNP U1, U2, U4/U6 and U5. This antibody raises against the full length of human SNRPE, and can recognize two bands of SNRPE, include a 9 kDa band(isoform) and a 11kDa band(SNRPE)
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References
- Pasternack SM, Refke M, Paknia E. Mutations in SNRPE, which encodes a core protein of the spliceosome, cause autosomal-dominant hypotrichosis simplex. American journal of human genetics. 92(1):81-7. 2013.
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