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Product Name
Human SNRPE Recombinant protein (GST tag)
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Description
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. {PubMed:18984161, PubMed:23246290, PubMed:23333303}.
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Protein name
Small nuclear ribonucleoprotein E
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Uniprot ID
P62304
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Gene Name
SNRPE
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human SNRPE (NP_003085.1) 1-92 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human SNRPE SDS-PAGE
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