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Product Name
Mouse SFRP4 (His Tag) recombinant protein
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Description
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake (By similarity).
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Protein name
Secreted frizzled-related sequence protein 4
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Protein short names
SFRP4; FRP-4; FRPHE; SFRP-4; MGC26498
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Uniprot ID
Q9Z1N6
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Gene Name
Sfrp4
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse sFRP4 (NP_057896.1) (Met 1-Ser 351) was expressed with a C-terminal polyhistidine tag.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse sFRP4 consists of 341 amino acids after removal of the signal peptide and has a predicted molecular mass of 39.4 kDa. In SDS-PAGE under reducing conditions, it migrates with an apparent molecular mass of 55-60 kDa due to glycosylation.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Mouse sFRP4 Protein (His Tag) SDS-PAGE
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