Anti-SFRP4 Rabbit antibody

Cat.#: 167349

Size:

Special Price 441.3 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Anti-SFRP4 Rabbit antibody
  • Documents
  • Description
    SFRP4 Rabbit polyclonal antibody
  • Tested applications
    WB, ICC/IF, FC
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    PYL; FRP-4; FRPHE; FRZB-2; sFRP-4 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human SFRP4
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/1000-1/5000

    ICC/IF: 1/20-1/50

    FC: 1/20

  • Validations

    Western blot detection of SFRP4 in K562,3T3,Hela cell lysates using SFRP4 Rabbit pAb(1:1000 diluted).Predicted band size:40kDa.Observed band size:53-55kDa.

    Western blot detection of SFRP4 in K562,3T3,Hela cell lysates using SFRP4 Rabbit pAb(1:1000 diluted).Predicted band size:40kDa.Observed band size:53-55kDa.

  • Background
    Swiss-Prot Acc.Q6FHJ7.Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types . SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling . Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake (PubMed:12952927).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"