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Product Name
S100A8 antibody
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Description
S100A8 Rabbit Polyclonal antibody. Positive WB detected in K-562 cells, A375 cells, A431 cells, A549 cells, COLO 320 cells, human serum tissue. Positive IHC detected in human stomach cancer tissue, human oesophagus tissue. Observed molecular weight by Western-blot: 9 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
60B8AG antibody; CAGA antibody; Calgranulin A antibody; Calprotectin L1L subunit antibody; CFAG antibody; CGLA antibody; CP 10 antibody; Cystic fibrosis antigen antibody; L1Ag antibody; MA387 antibody; MIF antibody; MRP 8 antibody; MRP8 antibody; NIF antibody; Protein S100 A8 antibody; S100A8 antibody; Urinary stone protein band A antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of S100A8 recombinant protein (Accession Number: NM_002964). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
K-562 cells were subjected to SDS PAGE followed by western blot with Catalog No:114965(S100A8 antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human stomach cancer using Catalog No:114965(S100A8 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human stomach cancer using Catalog No:114965(S100A8 antibody) at dilution of 1:100 (under 40x lens)
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Background
S100A8 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. S100A8 may form homodimer or heterodimer with S100A9(16216873).
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References
- Jiang GJ, Ma JY, Zhang GL. Protein profiling the differences between diabetic and normal mouse cumulus cells. Molecular reproduction and development. 81(12):1080-5. 2014.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"