• Rat IL23 (IL23A & IL12B Heterodimer) recombinant protein

Rat IL23 (IL23A & IL12B Heterodimer) recombinant protein

Cat.#: 504645

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Product Information

  • Product Name
    Rat IL23 (IL23A & IL12B Heterodimer) recombinant protein
  • Documents
  • Uniprot ID
    Q91Z84
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the rat IL23A (NP_569094.1) (Met1-Ala196) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the rat IL12B (EDM04146.1) (Met1-Ser335) was expressed with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids were co-expressed and the rat IL23A & the rat IL12B heterodimer was purified.
  • Protein Species
    Rat
  • Molecular weight
    The recombinant rat IL23A & the rat IL12B comprises 510 (186+324) amino acids and has a calculated molecular mass of 58.2 (21+37.2) KDa. The apparent molecular mass of the rat IL23A & the rat IL12B heterodimer is approximately 47.08, 43.29, 27.67 and 24.75 KDa respectively in SDS-PAGE.
  • Purity
    (17.9+53.5+2.9+23.8) % as determined by SDS-PAGE
  • Activity
    Measured by its ability to induce IL17 secretion by mouse splenocytes. The ED50 for this effect is 2-15 ng/mL.
  • Validations

    Rat IL-23 (IL23A & IL12B Heterodimer) Protein SDS-PAGE

    Rat IL-23 (IL23A & IL12B Heterodimer) Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"