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Product Name
Rat CDH13 / Cadherin-13 / H Cadherin recombinant protein
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Description
CDH13, also known as cadherin-13 and H Cadherin, is a member of the cadherin superfamily. CDH13 acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. CDH13 is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. CDH13 gene is hypermethylated in many types of cancer.
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Protein name
Cadherin 13
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Protein short names
P105; H-CADHERIN; TCAD; CDHH; CADHERIN 13; 4932416G01RIK; HEART CADHERIN; CDH13; CDHT; T-CAD; H-CADHERIN (HEART); T-CADHERIN
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Uniprot ID
Q8R490
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Gene Name
Cdh13; rCG_51389
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat CDH13 (NP_620244.1)(Met1-Ala692) was expressed with six amino acids (LEVLFQ) at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat CDH13 comprises 678 amino acids and predicts a molecular mass of 74.3 kDa. The apparent molecular mass of the recombinant protein is approximately 84-96 kDa in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Rat CDH13 / Cadherin-13 / H Cadherin Protein SDS-PAGE
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