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PSAP antibody

Cat.#: 114290

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Product Information

  • Product Name
    PSAP antibody
  • Documents
  • Description
    PSAP Rabbit Polyclonal antibody. Positive WB detected in PC-3 cells, HepG2 cells, L02 cells, MCF7 cells. Positive IHC detected in human prostate cancer tissue, human liver cancer tissue. Observed molecular weight by Western-blot: 58 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    A1 activator antibody; Cerebroside sulfate activator antibody; Co beta glucosidase antibody; Component C antibody; CSAct antibody; Dispersin antibody; FLJ00245 antibody; GLBA antibody; Glucosylceramidase activator antibody; Proactivator polypeptide antibody; prosaposin antibody; Protein C antibody; PSAP antibody; SAP 1 antibody; SAP 2 Saposin D antibody; SAP1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of PSAP recombinant protein (Accession Number: NM_002778). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:114290(PSAP antibody) at dilution of 1:800

    PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:114290(PSAP antibody) at dilution of 1:800

    Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using Catalog No:114290(PSAP Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using Catalog No:114290(PSAP Antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using Catalog No:114290(PSAP Antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using Catalog No:114290(PSAP Antibody) at dilution of 1:50 (under 40x lens)

  • Background
    proteins' (SAPs) that assist in the lysosomal hydrolysis of sphingolipids. After proteolytic processing of the presaposin protein, these 4 released polypeptides are functional activators. Saposin A was encoded by residues 60 to 143 of PSAP, saposin B by 195 to 275, saposin C by 311 to 390, and saposin D by 405 to 487. There are four 12-14 kDa heatstable glycoproteins. This antibody should recognize saposin B. Read more about this antibody on the blog:http://blog.ptglab.com/index.php/psap-antibody-uncovers-potential-role-of-prosaposin-in-cancer-survival/

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"