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Product Name
Mouse EGF/Epidermal Growth Factor recombinant protein
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Description
EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity).
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Protein name
Pro-epidermal growth factor
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Protein short names
EGF; URG; AI790464; HOMG4
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Uniprot ID
P01132
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Gene Name
Egf
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse EGF (P01132) (Asn977-Arg1029) was expressed and purified with two additional amino acids (Gly & Pro) at the N-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse EGF consists of 55 amino acids and predicts a molecular mass of 6.2 KDa. It migrates as an approximately 14 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells.
The ED50 for this effect is typically 0.1-0.6 ng/mL. -
Validations
Mouse EGF / Epidermal Growth Factor Protein SDS-PAGE
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