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Human PGF (Fc Tag) recombinant protein

Cat.#: 501281

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Product Information

  • Product Name
    Human PGF (Fc Tag) recombinant protein
  • Documents
  • Description
    Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
  • Protein name
    Placenta growth factor
  • Protein short names
    PGFL; AI854365; PLACENTA GROWTH FACTOR; VASCULAR ENDOTHELIAL GROWTH FACTOR-RELATED PROTEIN; MEMBER F; PGF; SHGC-10760; PLGF-2; D12S1900; PIGF; PLGF; PLACENTAL GROWTH FACTOR
  • Uniprot ID
    Q86TW6
  • Gene Name
    PGF; PGFL; PLGF
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human PGF (NP_002623.2) (Met1-Arg170) was expressed with the Fc region of mouse IgG1 at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human PGF consists 386 amino acids and predicts a molecular mass of 43.7 kDa.
  • Purity
    > 95 % as determined by SDS-PAGE.
  • Activity
    1. Measured by its binding ability in a functional ELISA.
    2. Immobilized human PGF-mFc at 10 μg/mL (100 μL/well) can bind human VEGFR1-His (Cat:503212). The EC50 of human VEGFR1-His (Cat:503212) is 0.19-0.43 μg/mL.
  • Validations

    Human PIGF / PLGF Protein (Fc Tag) SDS-PAGE

    Human PIGF / PLGF Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"