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Product Name
PLGF Polyclonal Antibody
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Description
Polyclonal antibody to PLGF
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Tested applications
WB, IHC
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Species reactivity
Human, Mouse
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Alternative names
PGF antibody; D12S1900 antibody; PGFL antibody; PIGF antibody; PLGF antibody; PlGF-2 antibody; SHGC-10760 antibody; placenta growth factor antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-170 of human PLGF (NP_002623.2).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:50 - 1:200 -
Validations
Western blot - PLGF Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using PLGF antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .
Immunohistochemistry - PLGF Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human colon using PLGF Antibody at dilution of 1:100 (40x lens).
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Background
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"