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Product Name
Mouse PGF recombinant protein
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Description
Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Also promotes cell tumor growth (By similarity).
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Protein name
Placenta growth factor
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Protein short names
PLACENTA GROWTH FACTOR; AI854365; PLACENTAL GROWTH FACTOR; PGF; VASCULAR ENDOTHELIAL GROWTH FACTOR-RELATED PROTEIN; PGFL; PIGF; PLGF; D12S1900; SHGC-10760; PLGF-2; MEMBER F
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Uniprot ID
P49764
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Gene Name
Pgf; Plgf
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse PGF (P49764) (Met1-Pro158) was fused with five amino acids (DDDDK) at the C-terminus was expressed and purified.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse PGF consists of 146 amino acids and has a calculated molecular mass of 16.6 kDa. The recombinant protein migrates as an approximately 28 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA. Immobilized mouse PGF at 10 μg/mL (100ul/well) can bind human VEGFR1-His (Cat:503212). The EC50 of human VEGFR1-His (Cat:503212) is 0.07-0.15 μg/mL.
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Validations
Mouse PIGF / PLGF Protein SDS-PAGE
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