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Product Name
Human Peroxiredoxin 1/PRDX1 (His Tag) recombinant protein
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Description
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).
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Protein name
Peroxiredoxin-1
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Protein short names
PRDXI; PEROXIREDOXIN 1; TPXA; PRX1; OSF-3; PAGB; RP23-177C18.2; PAG; MSP23; OSF3; PAGA; NKEF-A; PRXI; NKEFA; PRDX1; TDPX2; TDX2
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Uniprot ID
Q06830
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Gene Name
PRDX1; PAGA; PAGB; TDPX2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human PRDX1 (NP_002565.1) (Met 1-Lys 199) was expressed, with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human PRDX1 comprises 205 amino acids and has a predicted molecular mass of 22.9 kDa as estimated in SDS-PAGE under reducing conditions.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Human Peroxiredoxin 1 / PRDX1 Protein (His Tag) SDS-PAGE
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