Myelin basic protein antibody

Myelin basic protein antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Myelin basic protein Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue. Positive IHC detected in human brain tissue, human gliomas tissue. Observed molecular weight by Western-blot: 17-22 kDa

ELISA, WB, IHC

Human,Mouse,Rat; other species not tested.

MBP antibody; Myelin A1 protein antibody; Myelin basic protein antibody

Rabbit IgG

This antibody was obtained by immunization of Myelin basic protein recombinant protein (Accession Number: NM_001025090). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

MBP belongs to the myelin basic protein family. The classic group of MBP isoforms (isoform 4-isoform 14) are the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. This is a rabbit polyclonal antibody raised against the full-length of human MBP,and is capable of recognizing multiple isoforms of MBP.