Human MBP Recombinant protein (GST tag)

Cat.#: 509820

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Product Information

  • Product Name
    Human MBP Recombinant protein (GST tag)
  • Documents
  • Description
    The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation. {PubMed:8544862}.
  • Protein name
    Myelin basic protein
  • Uniprot ID
    P02686
  • Gene Name
    MBP
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human MBP (NP_001020272.1) 134-304 aa was fused with the N-terminal GST tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human MBP(Full length) SDS-PAGE

    Recombinant human MBP(Full length) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"