• Mouse Serpind1/Hcf2/Hcii (His tag) recombinant protein

Mouse Serpind1/Hcf2/Hcii (His tag) recombinant protein

Cat.#: 518047

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Product Information

  • Product Name
    Mouse Serpind1/Hcf2/Hcii (His tag) recombinant protein
  • Documents
  • Description
    SerpinD1, also known as heparin cofactor II(HC-II), is a member of Serpin superfamily of the serine proteinase inhibitors. It is a single chain glycoprotein with a size of 66.5 kDa and is secreted from hepatocytes. HC-II acts as a thrombin inhibitor in the coagulation cascade, in a glycosaminoglycan-dependent pathway using the release of a sequestered hirudin-like N-terminal tail for interaction with thrombin. This serpin belongs to multiple member group V2 of vertebrate serpin classification. It has been suggested that HC-II is a predictor of decreased atherosclerosis in the elderly and protective against atherosclerosis in mice. HCII can used as a predictive biomarker and therapeutic target for atherosclerosis.
  • Protein name
    serine (or cysteine) peptidase inhibitor, clade D, member 1(Serpind1)
  • Protein short names
    Hcf2; Hcii
  • Uniprot ID
    P49182
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Mouse Serpind1/Hcf2/Hcii Glu24-Ser478 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Mouse
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Mouse Serpind1/Hcf2/Hcii (His tag) recombinant protein

    Mouse Serpind1/Hcf2/Hcii (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"