Human SerpinD1 (His Tag) recombinant protein

Cat.#: 503095

Size:

Special Price 532.2 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Human SerpinD1 (His Tag) recombinant protein
  • Documents
  • Description
    Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner.
  • Protein name
    Heparin cofactor 2
  • Protein short names
    SERPIND1; MGC107662; LS2; HCII; D22S673; AA985900; HLS2; HC2; AI303446; HCF2
  • Uniprot ID
    Q8IVC0
  • Gene Name
    SERPIND1; HCF2
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human SerpinD1 precursor (NP_000176.2) (Met 1-Ser 499) was expressed with a C-terminal polyhistidine tag.
  • Protein Species
    Human
  • Molecular weight
    The mature recombinant human SerpinD1 consists of 491 amino acids and predicts a molecular mass of 56.4 kDa. By SDS-PAGE under reducing conditions, the apparent molecular mass of rhSerpinD1 is approximately 65-70 kDa as a result of glycosylation.
  • Purity
    > 97 % as determined by SDS-PAGE
  • Activity
    Measured by its binding ability in a functional ELISA.
    Immobilized recombinant human SerpinD1-His (Cat:503095) at 10 μg/ml (100 μl/well) can bind biotinylated recombinant mouse ELANE-His (Cat:50204-M08H) with a linear range of 0.15-10.0 μg/ml.
  • Validations

    Human SerpinD1 Protein (His Tag) SDS-PAGE

    Human SerpinD1 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"