Mouse NOTCH1 (His Tag) recombinant protein

Cat.#: 503731

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Product Information

  • Product Name
    Mouse NOTCH1 (His Tag) recombinant protein
  • Documents
  • Protein name
    Neurogenic locus notch homolog protein 1
  • Protein short names
    TAN1; 9930111A19RIK; AOS5; MIS6; NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1; LIN-12; MOTCH A; HN1; MAJOR TYPE A PROTEIN; RP23-306D20.12-001; AOVD1; N1; MT14
  • Uniprot ID
    Q01705
  • Gene Name
    Notch1; Motch
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mouse NOTCH1 (NP_032740.3) N-terminal fragment (Met 1-Gln 526) was expressed?with a C-terminal polyhistidine tag.
  • Protein Species
    Mouse
  • Molecular weight
    The secreted recombinant mouse NOTCH1 (aa 1-526) consists of 518 amino acids and has a calculated molecular mass of 55 kDa. It migrates as an approximately 80 KDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 82 % as determined by SDS-PAGE
  • Activity
    1. Measured by its binding ability in a functional ELISA.
    2. Immobilized human DLL4 (cat: 503992) at 10 μg/mL (100 μl/well) can bind biotinylated mouse NOTCH1-his, The EC50 of biotinylated mouse NOTCH1-his is 40 ng/mL.
    3. Immobilized mouse DLL4-his (Cat:502366) at 10 μg/mL (100 μl/well) can bind biotinylated mouse NOTCH1-his, The EC50 of biotinylated mouse NOTCH1-his is 30 ng/mL.
  • Validations

    Mouse Notch-1 / NOTCH1 Protein (His Tag) SDS-PAGE

    Mouse Notch-1 / NOTCH1 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"