Mouse Ngfr (Fc tag) recombinant protein

Mouse Ngfr (Fc tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Mouse Tumor necrosis factor receptor superfamily member 16(TNFRSF16) is a single-pass type I membrane protein which contains 1 death domain and 4 TNFR-Cys repeats. It has low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. It can mediate cell survival as well as cell death of neural cells. TNFRSF16 plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. It binds to rabies virus glycoprotein Gs. Necessary for the circadian oscilllation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.

nerve growth factor receptor (TNFR superfamily, member 16)(Ngfr)

Q8CFT3

Human Cells

A DNA sequence encoding the Mouse Ngfr Gly20-Asn243 is expressed with a Fc tag at the C-terminus.

Mouse

>95% as determined by SDS-PAGE.