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Product Name
Anti-NGFR antibody
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Description
Mouse monoclonal antibody to NGFR
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Tested applications
WB, IP, IF
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Species reactivity
Human, Mouse, Rat
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Alternative names
CD271 antibody; p75NTR antibody; TNFRSF16 antibody; p75(NTR) antibody; Gp80-LNGFR antibody
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Isotype
Mouse IgG1
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Preparation
This antigen of this antibody was amino acids 393-427 at the c-terminus of ngfr p75 of human origin.
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Clonality
Monoclonal
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Formulation
Liquid, 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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Storage instructions
Store at +4℃
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Applications
WB: 1:100-1:1,000
IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
IF: 1:50-1:500
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Validations
Fig1: Westernblot analysis of NGFR p75 expressionin SK-N-NC whole cell lysate.
Fig2: Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.
- Background
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References
- McKay, S.E., et al. 1996. The expression of Trk B and p75 and the role of BDNF in the developing neuromuscular system of the chick embryo. Development 122: 715-724.
- Hempstead, B.L., et al. 1991. High-affinity NGF binding requires coexpression of the Trk proto-oncogene and the low-affinity NGF receptor. Nature 350: 678-683.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"