• Mouse Gzmb/Ctla-1/Ctla1 (His tag) recombinant protein

Mouse Gzmb/Ctla-1/Ctla1 (His tag) recombinant protein

Cat.#: 518043

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Product Information

  • Product Name
    Mouse Gzmb/Ctla-1/Ctla1 (His tag) recombinant protein
  • Documents
  • Description
    Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
  • Protein name
    granzyme B(Gzmb)
  • Protein short names
    Ctla-1; Ctla1
  • Uniprot ID
    P04187
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Mouse Gzmb/Ctla-1/Ctla1 Gly19-Ser247 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Mouse
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Mouse Gzmb/Ctla-1/Ctla1 (His tag) recombinant protein

    Mouse Gzmb/Ctla-1/Ctla1 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"