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Product Name
Mouse Gzmb/Ctla-1/Ctla1 (His tag) recombinant protein
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Description
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
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Protein name
granzyme B(Gzmb)
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Protein short names
Ctla-1; Ctla1
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Uniprot ID
P04187
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Mouse Gzmb/Ctla-1/Ctla1 Gly19-Ser247 is expressed with a 6His tag at the C-terminus.
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Protein Species
Mouse
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Purity
>95% as determined by SDS-PAGE.
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Validations
Mouse Gzmb/Ctla-1/Ctla1 (His tag) recombinant protein
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