Mouse EPHA3/Eph Receptor A3 (His Tag) recombinant protein

Mouse EPHA3/Eph Receptor A3 (His Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.

Receptor protein-tyrosine kinase

TYROSINE-PROTEIN KINASE RECEPTOR ETK1; AW492086; ETK1; EK4; HEK; CEK4; MEK4; EPHRIN TYPE-A RECEPTOR 3; ETK; HUMAN EMBRYO KINASE 1; EPH-LIKE TYROSINE KINASE 1; EPHA3; END3; EPH-LIKE KINASE 4; TYRO4; HEK4; TYRO4 PROTEIN TYROSINE KINASE; EPH RECEPTOR A3; TYROSINE-PROTEIN KINASE TYRO4

Q8BRB1

Epha3

Human Cells

A DNA sequence encoding the mouse EPHA3 (NP_034270.1) (Met1-His541) was expressed with a C-terminal polyhistidine tag.

Mouse

The recombinant mouse EPHA3 comprises 532 amino acids and has a predicted molecular mass of 60.2 kDa.

> 95 % as determined by SDS-PAGE

1. Measured by its binding ability in a functional ELISA.
2. Immobilized mouse EPHA3-His at 10 μg/mL (100 μL/well) can bind mouse EFNA5-Fc (Cat:502960). The EC₅₀ of mouse EFNA5-Fc (Cat:502960) is 4.9-11.4ng/mL.