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Product Name
Rat CD14 (His Tag) recombinant protein
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Description
In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (By similarity).
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Protein name
Monocyte differentiation antigen CD14
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Protein short names
MONOCYTE DIFFERENTIATION ANTIGEN CD14; CD14 ANTIGEN; CD14
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Uniprot ID
Q63691
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Gene Name
Cd14
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat Cd14 (Q63691) (Met1-Tyr341) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat Cd14 consists 335 amino acids and predicts a molecular mass of 36.7 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Rat CD14 Protein (His Tag) SDS-PAGE
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