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Product Name
liver Arginase antibody
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Description
liver Arginase Mouse Monoclonal antibody. Positive IHC detected in human liver tissue, human liver cancer tissue. Positive WB detected in HepG2 cells. Observed molecular weight by Western-blot: 36 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
Arginase 1 antibody; liver Arginase antibody; Liver type arginase antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of liver Arginase recombinant protein (Accession Number: BC005321). Purification method: Protein G purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:107406(ARG1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver slide using Catalog No:107406(ARG1 Antibody) at dilution of 1:50
Immunohistochemistry of paraffin-embedded human liver slide using Catalog No:107406(ARG1 Antibody) at dilution of 1:50
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Background
Liver arginase(Arginase-1) belongs to the arginase family. Hepatic arginase 1 is closely associated with alternative macrophage activation(PMID:12098359) and Arg1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia (ARGIN).
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