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Product Name
Human CD47 recombinant protein
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Description
Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
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Protein name
Leukocyte surface antigen CD47
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Protein short names
ANTIGENIC SURFACE DETERMINANT PROTEIN OA3; AA407862; INTEGRIN-ASSOCIATED SIGNAL TRANSDUCER; INTEGRIN-ASSOCIATED PROTEIN; INTEGRIN-ASSOCIATED SIGNAL TRANSDUCER); MER6; CD47 GLYCOPROTEIN; 9130415E20RIK; LEUKOCYTE SURFACE ANTIGEN CD47; IAP; INTEGRIN ASSOCIATED PROTEIN; RH-RELATED ANTIGEN; B430305P08RIK; OA3; AI848868; AW108519; CD47 ANTIGEN (RH-RELATED ANTIGEN; ANTIGEN IDENTIFIED BY MONOCLONAL ANTIBODY 1D8; ITGP
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Uniprot ID
Q08722
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Gene Name
CD47; MER6
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human CD47 (NP_942088.1) (Met1-Pro139) was expressed with six amino acids (LEVLFQ) at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CD47 consists 128 amino acids and predicts a molecular mass of 14.5 kDa.
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Purity
> 90 % as determined by SDS-PAGE.
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Validations
Human CD47 Protein
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