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Human IL31/Interleukin-31 (His Tag) recombinant protein

Cat.#: 502103

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Product Information

  • Product Name
    Human IL31/Interleukin-31 (His Tag) recombinant protein
  • Documents
  • Description
    Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.
  • Protein name
    Interleukin-31
  • Protein short names
    INTERLEUKIN 31; IL-31; 1700013B14RIK; IL31
  • Uniprot ID
    Q6EBC2
  • Gene Name
    IL31
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human IL31 (NP_001014358.1) (Met1-Thr164) was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human IL31 consists of 152 amino acids and predicts a molecular mass of 17.3 KDa. It migrates as an approximately 31.8 KDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to induce STAT3 activation in U‑87 cells.
    The ED50 for this effect is 11-45 ng/mL.
  • Validations

    Human IL-31 / IL31 Protein (His Tag) SDS-PAGE

    Human IL-31 / IL31 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"