-
Product Name
Recombinant Human IL-31 protein (His tag)
- Documents
-
Description
Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR; May function in skin immunity;
-
Protein short names
IL31
-
Uniprot ID
Q6EBC2
-
Gene Name
interleukin 31
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the human IL31 (NP_001014358.1) (Met1-Thr164) was expressed with a polyhistidine tag at the C-terminus.
-
Protein Species
Human
-
Molecular weight
The recombinant human IL31 consists of 152 amino acids and predicts a molecular mass of 17.3 KDa. It migrates as an approximately 31.8 KDa band in SDS-PAGE under reducing conditions due to glycosylation.
-
Purity
> 95 % as determined by SDS-PAGE
-
Activity
Measured by its ability to induce STAT3 activation in U‑87 cells. The ED50 for this effect is 11-45 ng/mL.
-
Validations
Recombinant Human IL-31 protein (His tag)
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"