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Product Name
Canine IL13RA2 / CD213A2 (Fc Tag) recombinant protein
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Description
Binds as a monomer with high affinity to interleukin-13 (IL13).
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Protein name
Interleukin-13 receptor subunit alpha-2
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Protein short names
CD213A2; CT19; IL-13R; IL13RA2; IL13BP
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Uniprot ID
Q95LF0
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Gene Name
IL13RA2
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the canine IL13RA2 (NP_001003075.1) (Met1-Thr338) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Canine
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Molecular weight
The recombinant canine IL13RA2/Fc is a disulfide-linked homodimer. The reduced monomer comprises 558 amino acids and has a predicted molecular mass of 64.1 kDa. The apparent molecular mass of the protein is approximately 66-72 kDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Measured by its ability to inhibit IL13 dependent proliferation of TF-1 human erythroleukemic cells.
The ED50 for this effect is typically 0.01-0.04 μg/mL. -
Validations
Canine IL13RA2 / IL13R Protein (Fc Tag) SDS-PAGE
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